Assassin's Blade is a skill located in the Assassination (which can be found in the Nightblade skill tree). Assassin's Blade is a base skill, and can be morphed into Killer's Blade or Impale.
Assassin's Blade deals the following types of damage: Magic Damage. Which means that it gets buffed by the following blue champion point trees: Elemental Expert, Elf Born, Master at Arms, Spell Erosion. Also the following red champion point trees protect against this skill: Elemental Defender, Iron Clad.